American Journal of Pharmacy and Health Research

ABSTRACTSARSCoV2 infection has caused and will continue to cause considerable human suffering. Research on the pathogenesis of viruses has yielded consistent results from various tests of virus entry and spread to the host. These studies also revealed a strong association between harmless inflammations, aging and metabolic disorders, and SARSCoV2 infection and its prognosis. Diet helps regulate inflammation, and nutritious foods can inhibit the entry of viruses. Therefore, we have compiled the literature on antiviral health products that are effective against other similar coronaviruses. The purpose of this study is to comprehensively review the available information about the antiviral activity of nutritious foods and discuss the impact of these findings on the design of diets that can enhance innate immunity and prevent COVID19. This review emphasizes the fundamental impact of nutritious food and diet on inhibiting virus entry, and provides a new perspective for the prevention and treatment of COVID19. Keywords: SARSCoV2, diet, plant protease inhibitors, polyphenols, biologically active peptides

ABSTRACTMass Spectrometry- It is an analytical technique that generates charged particles in the form of ions from the substance to be analyzed to measure its mass to charge ratio. Ion Source plays an important role for generation of charged ions which further travels through analyzer and ends at detector. The production of intact molecular ions can be achieved under adequate experimental conditions, with minimal fragmentation known as soft ionization method. Neutral species either loss or gain of charge to generates ions. This paper covers an information about various type of mass ion Source (Electron impact, Chemical ionization and field ionization, Desorption-Field desorption, Electro spray ionization, matrix assisted desorption ionization, Plasma desorption) are in use for mass spectroscopy. Ions get affected by change in electrical, magnetic and radiofrequency effect as they containing either positive or negative charges this leads to better resolution of ions.Keywords: Mass Spectroscopy, Ion source, Ionization, Desorption.

ABSTRACTParkinson’s disease (PD) is neurodegenerative disorder that affects predominantly dopamine producing neurons in a specific area of the brain called substantia nigra. Parkinson’s disease is associated with risk factors including aging, family history, pesticide exposure and environmental chemicals. Its ultimate causes are unknown. Characterized by both motor and non motor symptoms. Recent decades have witnessed a proliferation of medical pharmacological therapies and innovative surgical interventions like deep brain stimulation (DBS).Exercise is important for people with PD because it helps to maintain balance, mobility and the ability to perform daily routines.  This review mainly highlights the etiology, clinical features, diagnosis and treatment (pharmacological and non pharmacological therapies) of peoples with Parkinson’s disease.Keywords: Parkinson’s disease, Neurodegenerative disorder, Deep Brain Stimulation (DBS), Diagnosis and Treatment.