ISSN 2321–3647
Sun, 19 Nov 2017

Monitoring of Lipid Profile in Diabetic Mellitus Type 2 Patients Controlled and Uncontrolled in Sana’a, Yemen

Qais Abdu Alwareth 1 , Saeed AL-Shaibany 1 , Mohammed Amood AL-Kamarany 2,3 *, Ali AL-Meery 1 , Ibtisam AL-Zabidy1

1.Biochemistry  Department, Faculty of Medicine and Health Sciences, Sana’a  University, Yemen

2.Department of Pharmacy Practice, Faculty of Clinical Pharmacy ,  Hodeidah University,

3.Tihama foundation for medical - pharmaceutical studies and research, Hodeidah, Yemen


ABSTRACT

Diabetic Milletus(DM).is the most frequent endogenous cause of fat metabolism- disorder. Therefore, the study aims to monitor the lipid profile  in  DM type 2 patients controlled and uncontrolled in Sana’a , Yemen. The study included 150 subjects from major public hospitals in Sana'a city, Yemen. 50 were diagnosed with DM type 2 controlled as group I and 50 were diagnosed with DM type 2 uncontrolled as group II. 50 subjects were healthy volunteers as control group. The biochemical parameters namely Fasting Blood Sugar (FBG) , and Glycelated Hemoglobin (HBA1c) were assayed in three groups. Data obtained were analyzed using suitable statistical tools. The lipid profile namely total cholesterol  mg/dl , triglyceride mg/dl HDL mg/dl, and LDL mg/ were assayed in DM type 2   controlled and uncontrolled and compared with control healthy group. The results were  described namely (166 ± 31 mg/dl ; 196 ± 50 ; 131 ± 28 ) , (146± 60 mg/dl ; 193 ± 94 ; 92 ± 30 ) , (37± 8.2 mg/dl , 36 ± 14, 42 ± 12 ), and (80 ± 25 mg/dl , 95 ± 30 , 76 ± 25) respectively.   According to above results , non different significant (p > 0.05) in all parameters of lipid profile was observed between DM  type 2  controlled and uncontrolled groups . while the results were observed different significant (p < 0.05) in serum levels of total cholesterol , triglyceride and LDL between controlled and healthy group and also non - different significant (p > 0.05) in serum levels of HDL between both . In addition, different significant (p > 0.05) in all parameters of lipid profile was observed between uncontrolled and control healthy groups .The study outcome concluded  that the hyperlipidemia may progressive in DM type 2 patients uncontrolled.

Keywords: Diabetic mellitus, type 2 , lipid profile , insulin resistance ,  controlled , uncontrolled 


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