ISSN 2321–3647
Sat, 18 Nov 2017

Arsenic Trioxide induced Hepatotoxicity in Rats - Protective role of Alcoholic Leaf Extracts of Annona squamosa

M. Nagalingam1, G. Arumugam1, N. Henita Geo1, A. Panneerselvam1*

1.Department of Zoology, Thiruvalluvar University, Serkkadu, Vellore-115


ABSTRACT

Liver is the largest gland in the human body. Liver performs various vital functions in our system. The liver breaks down toxic substances and most metals products in a detoxifying manner. The present study was conducted to evaluate the hepatoprotective effects of an alcoholic leaf extract of Annona squamosa on Arsenic Trioxide induced liver damage in albino rats. Wistar albino rats weighing around 180-200g were used. Blood and liver tissue were collected for the assessment of serum marker enzymes such as ALT, AST and ALP.

Keywords: Annona squamosa, Arsenic, Albino rats, Biochemical tests, Histological studies

 


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