ISSN 2321–3647
Sun, 19 Nov 2017

Comparative Study of Prednisolone Acetate 1% Eye Drop With Difluprednate 0.05% Eye Drop In Postoperative Management Following Small Incision Cataract Surgery

Ashok Kumar Meena1*, Mukul Jain2

1.Professor & HOD, Department of Ophthalmology, Govt. Medical College, Kota, Rajasthan, India

2. P.G. Resident Doctor, Department of Ophthalmology, Govt. Medical College, Kota, Rajasthan, India


This study was done to compare the anti-inflammatory efficacy of prednisolone acetate 1% and difluprednate 0.05% eye drops in the management of ocular inflammation after uneventful small incision cataract surgery. It was a prospective randomized control study done in Department of Ophthalmology, Government Medical College & associated group of hospitals, Kota. 100 patients (age >50 years) with senile cataract were taken. After surgery, 50 patients were treated with prednisolone acetate 1% and 50 patients with difluprednate 0.05% eye drops. Patients were examined and compared on postoperative day 1, 3, 7 & 28 for pain, circumcorneal congestion, corneal oedema, aqueous flare, visual acuity and intraocular pressure. Reduction in pain, ciliary congestion, corneal oedema and aqueous flare on day 7 was more in difluprednate group. No clinically significant elevation in intraocular pressure was noted in any patient during study. Difluprednate 0.05% controls postoperative inflammation rapidly as compared to prednisolone acetate 1%.

Keywords: Prednisolone, Difluprednate, Aqueous flare, intraocular pressure

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