ISSN 2321–3647
Sat, 18 Nov 2017

Phytochemical Screening and In vivo Evaluation of Anti inflammatory Activity of Fruits of Lagerstroemia speciosa L

Prasenjit Das1*, Asish Bhaumik2*, Rabindra Tripura1, Sanjoy Das1, R. Nagababu2

1. Department of Pharmaceutical Chemistry, Regional Institute of Pharmaceutical Science and Technology, Abhoynagar, Agartala-799005, India.

2. Department of Pharmaceutical Chemistry, Teja College of Pharmacy, Kodad, Nalgonda-508206, Telangana State, India.


ABSTRACT

Jarul (it is also known as Banaba) is a flowering plant that grows in warm climate like the Philippines, India and others.In India, Jarul  is also used in Ayurvedic medicine for the treatment of diabetes. The Jarul leaves and flowers contain corrosolic acid, a substance being studied for its insulin like effect of lowering the glucose in the body. Jarul is also being studied as a weight-loss supplement for its ability to delay or reduce the absorption of carbohydraes. Jarul is also rich in vitamins and minerals including zinc and magnesium. Jarul is also rich in dietary fibers. The scientific name the Jarul or Banaba is Lagerstroemia speciosa L (Lythraceae). The main objective of the present work is to evaluate the Antiinflammatory activity of fruits seeds of Lagerstroemia speciosa L. Based on this, a new series of constituents had been planned to extract by Ethanol (ELN),Methanol (MLN), Acetone (ACT)and Chloroform (CLF)from the fruit seeds of  Lagerstroemia speciosa L. The in-vivo Anti-inflammatory activity was carried out by carrageenan induced paw edema method in rats. The present experimental data displayed that all the extracts exhibited mild to good anti-inflammatory activity. All the extracts exhibited highest Anti-inflammatory activity at 120 min with the percentage protection of 63.18% (ELN), 48.95% (MLN), 44.95%(ACT) and 65.5%(CLF). Among these four extracts ELN and CLF displayed the highest antiinflammatory activity.

Keywords: Lagerstroemia speciosa L, anti-inflammatory activity, Carrageenan, Paw edema.


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