ISSN 2321–3647
Sat, 18 Nov 2017

Cyclophosphomide Induced Recurrent Urinary Tract Infection and Pancytopenia in Lupus Nephritis Patient

Sudhakar Reddy1*, Yasaswini Bandlamudi1, Ahamada Safna Mariyam.M2

1. Pharm.D Interns, Nandha College of Pharmacy, Erode

2. Acharya & B.M Reddy College of Pharmacy, Bangalore.


ABSTRACT

Lupus nephritis occurs about 30-40% of adult with Systemic Lupus Erythematosus and associated with increased morbidity and mortality. Focal and diffuse proliferative forms of lupus nephritis are known to progress to chronic renal failure unless treated by immunosuppressive drugs. Lupus nephritis remains a major cause of deaths among patients of Hispanic and African-American ethnicity. Generally renal involvement is more common in blacks, Indians and Chinese, with less prevalence Caucasians and Arabs. Cyclophosphamide and glucocorticoids are considered to be the standard care for the patients with proliferative lupus nephritis. Intravenous Cyclophosphamide use is limited due to its potentially severe toxic effects. Here we report a case of Cyclophosphamide induced recurrent occurrence of Urinary Tract Infection and Pancytopenia in lupus nephritis patients and it was treated by using the Mycofenolate Mofetil and Prednisolone.

Keywords: Lupus Nephritis, Systemic Lupus Erythematosus, Cyclophosphamide, Urinary Tract Infection and Pancytopenia.


[PDF]  Viewed: 657  Downloaded: 97
  • Call for paper
    Call for paper

    American Journal of Pharmacy and Health Research (AJPHR) is a peer-reviewed, monthly official international journal allowing access to abstracts and full-text.

  • Email & SMS Alerts
    Email & SMS Alerts

    Email/SMS alert system is one of the key features and gives update information about the submitted manuscript.

    Read more...

  • Article Statastics
    Article Statastics

    American Journal of Pharmacy and Health Research (AJPHR) provides unique facility for authors to know popularity of articles on basis of numbers of PDF download and views. It will display in tabulated format.

  • Online Submission
    Online Submission

    American Journal of Pharmacy and Health Research (AJPHR) is one of the International open access journal devoted to various disciplines in science and technology.

    Read more...

web counter
web counter