ISSN 2321–3647
Sat, 18 Nov 2017

New UV-Spectrophotometric Method Development and Validation for the Assay of Cilostazol in Pure and Formulations

Suresh T1, Rambabu K1*

1. Department of Chemistry, RVR &JC College of Engineering, Chowdavaram, Guntur, AP, India.


A simple, new UV-spectrophotometric method has been developed and validated for the assay of cilostazol in pure and formulations based on measurement of absorption at maximum wavelength of 257.40nm. The developed method exhibited linearity in the range 2.5-15μg/ml with precision is exemplified by relative standard deviation of 0.86% for cilostazol. The percentage mean recovery of cilostazol was found to be in the range of 98.39‐99.34% during accuracy studies respectively. The proposed method is further validated statistically in accordance with ICH norms and the validation results allowed the feasibility of the proposed method in the analysis of cilostazol in pure and its formulations.

Keywords: Cilostazol, Formulation’s, ICH norm’s.

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