ISSN 2321–3647
Sat, 18 Nov 2017

Comparison of Analgesic Efficacy of Diclofenac Sodium, Ketorolac and Tramadol after Laparoscopic Cholecystectomy

Tanveer Ahmed Khan1*, Sikandar Ali Zar1, LubnaShakir1, Iftikhar AhmadHotiana2

1. Faculty of Pharmacy, Hajvery University, Lahore-Pakistan.

2. Jinnah Hospital, Lahore-Pakistan.


The aim of this study was to compare the analgesic efficacy of diclofenac sodium, ketorolac, tramadol individually and their combination after laparoscopic cholecystectomy. Total 150 subjects who met the inclusion and exclusion criteria were randomly (lottery method) divided into five groups to receive respective treatment. Pain score was measured after 1, 2, 4, 6, 12, 24 and 48 hours after surgery through visual analogue scale. The data was statistically analyzed through SPSS (version 20.0). It is concluded on the basis of collected results that a combination of Non-Steroidal Anti-inflammatory Drugs and Opioid derivatives is much superior to achieve effective pain control than either of the drug alone. Furthermore, ketorolac and tramadol combination provided more efficient pain control than diclofenac sodium and tramadol combination. This effective pain control is associated with short hospital stay which will cause less economic burden for patients. So, we may recommend that Non-Steroidal Anti-inflammatory Drugs (ketorolac) and opioids (tramadol) combination should be used for effectual pain control after laparoscopic cholecystectomy.

Keywords: Diclofenac, Ketorolac, Tramadol, Cholecystectomy.

[PDF]  Viewed: 1107  Downloaded: 177
  • Call for paper
    Call for paper

    American Journal of Pharmacy and Health Research (AJPHR) is a peer-reviewed, monthly official international journal allowing access to abstracts and full-text.

  • Email & SMS Alerts
    Email & SMS Alerts

    Email/SMS alert system is one of the key features and gives update information about the submitted manuscript.


  • Article Statastics
    Article Statastics

    American Journal of Pharmacy and Health Research (AJPHR) provides unique facility for authors to know popularity of articles on basis of numbers of PDF download and views. It will display in tabulated format.

  • Online Submission
    Online Submission

    American Journal of Pharmacy and Health Research (AJPHR) is one of the International open access journal devoted to various disciplines in science and technology.


web counter
web counter