ISSN 2321–3647
Sun, 19 Nov 2017

UV-Spectrophtometric Assay Method for the Assay of Tolterodine in Pure and Formulations

Siva Shankar Rao G1, P.S.Sarat1, Ramachandran D1*

1. Department of Chemistry, Acharya Nagarjuna University,Guntur,AP,India.


ABSTRACT

A simple, cost effective and reproducible UV-spectrophotometric method has been developed and validated for the assay of Tolterodine in pure and dosage forms. This assay is based on measurement of absorption at maximum wavelength of 282nm. Beer’s law of this proposed method was obeyed in the concentration range of 60-120μg/mL with regression equation of y = 0.0068x-0.0117 and with correlation coefficient of 0.9988 respectively. The percentage recovery of tolterodine ranged from 99.93- 100.37 in pharmaceutical dosage form. The results of the analysis for linearity, accuracy (recovery), precision and specificity were validated statistically and by recovery studies in accordance with ICH norms.

Keywords: Tolterodine, UV-Spectrophotometry.


[PDF]  Viewed: 664  Downloaded: 103
  • Call for paper
    Call for paper

    American Journal of Pharmacy and Health Research (AJPHR) is a peer-reviewed, monthly official international journal allowing access to abstracts and full-text.

  • Email & SMS Alerts
    Email & SMS Alerts

    Email/SMS alert system is one of the key features and gives update information about the submitted manuscript.

    Read more...

  • Article Statastics
    Article Statastics

    American Journal of Pharmacy and Health Research (AJPHR) provides unique facility for authors to know popularity of articles on basis of numbers of PDF download and views. It will display in tabulated format.

  • Online Submission
    Online Submission

    American Journal of Pharmacy and Health Research (AJPHR) is one of the International open access journal devoted to various disciplines in science and technology.

    Read more...

web counter
web counter