ISSN 2321–3647
Tue, 26 Sep 2017

Role of Glutathione-S-Transferase gene susceptibility in patient with Bronchial asthma

Chandan Kumar1 , Priyanka Gaur1, Sarika Pandey2, Bhattacharya S*1

1.Department of Physiology King George's Medical University, Lucknow

2.Department of Pulmonary Medicine King George's Medical University, Lucknow


Asthma is one of the most common chronic diseases in the world which can cause considerable morbidity and a significant mortality.  Hence it is important to find out the different molecular diagnostic marker which can be use for early detection as well as treatment of patient with bronchial asthma.  GST biomarkers is likely become important not only as risk factors in the pathogenesis of asthma but also as determinants of responsiveness to treatment. This review represents the evidence reported  the association between gene polymorphism of glutathione-s-transferases (GSTs) GSTP1, GSTM1, GSTT1 gene and bronchial asthma. The data of Indian scenario demonstrate that the Polymorphism of Glutathione-s-transferase gene GSTT1, GSTM1 and GSTP1 is not significantly associated with Bronchial asthma in northern Indian population due to low sample size.

Keywords: Bronchial Asthma; GST; Polymorphism


[PDF]  Viewed: 972  Downloaded: 164
  • Call for paper
    Call for paper

    American Journal of Pharmacy and Health Research (AJPHR) is a peer-reviewed, monthly official international journal allowing access to abstracts and full-text.

  • Email & SMS Alerts
    Email & SMS Alerts

    Email/SMS alert system is one of the key features and gives update information about the submitted manuscript.


  • Article Statastics
    Article Statastics

    American Journal of Pharmacy and Health Research (AJPHR) provides unique facility for authors to know popularity of articles on basis of numbers of PDF download and views. It will display in tabulated format.

  • Online Submission
    Online Submission

    American Journal of Pharmacy and Health Research (AJPHR) is one of the International open access journal devoted to various disciplines in science and technology.


web counter
web counter