ISSN 2321–3647
Sat, 18 Nov 2017

Association of Glycosylated Haemoglobin to Red Blood Corpuscles Indices

Rajeswari S1, Anila Mathan2 &Swaminathan S3

1 Junior Technical Officer, Department of Biochemistry, Lab Services

2 Senior Consultant& Head,  Department of Haematology and Transfusion Medicine, Lab Services

3 Senior Consultant& Head,  Department of Biochemistry, Lab Services


ABSTRACT

Variations in Red Blood Corpuscles indices survival can cause clinically important differences in Glycosylated Haemoglobin levels. Many previous studies have shown that Glycosylated Haemoglobin levels did not correlate with the degree of anemia for a given mean plasma glucose and hence Glycosylated Haemoglobin level in patients with iron deficiency anemia should be interpreted with caution.  Glycosylated Haemoglobin level is not affected by degree of anemia or glucose level alone but red blood corpuscles indices, notably Mean Corpuscular Haemoglobin, Mean Corpuscular Haemoglobin Concentration, Platelet Distribution Width, Red Cell Distribution Width & White Blood Cells. fractions may affect. This study has proved that all the above indices are significantly correlated to Glycosylated Haemoglobin levels, thus giving an understanding that Glycosylated Haemoglobin levels in Diabetes with iron deficiency anemia could be interpreted with Red Blood Corpuscles indices.

Keywords: Anemia, Glycosylated Haemoglobin, Red Blood Corpuscles , Platelet Distribution Width, White Blood Corpuscles.

 


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