ISSN 2321–3647
Sun, 19 Nov 2017

IR Quantification of Isoniazid In Bulk and Oral Dosage Form

V.Niraimathi*1, A. Jerad Suresh1, R.Ramaprabha1, I.Senthil Kumar1

1.Department of Pharmaceutical Chemistry, College of Pharmacy, Madras Medical College, Chennai 600003,Tamilnadu, India.


ABSTRACT

Simple and sensitive infrared  spectrophotometric method have been developed for the estimation of  isoniazid in tablet dosage form and the Beer’s concentration range was found to be 0.5mg-2.0 mg. The correlation coefficient for the method was found to be 0.9 and the developed method was analyzed for specificity, linearity of response, precision and accuracy; thus the proposed method could be adopted for routine analysis of bulk drug and its formulation.

Keywords: Infrared spectroscopy (IR), Potassium thiocyanate(KSCN), Potassium bromide disc. 


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