ISSN 2321–3647
Sat, 18 Nov 2017

Synthesis of Some γ-Benzopyrone Derivatives as Analgesic Agents

Sukhen Som1*, Jayaveera K. N2

1. Department of Pharmaceutical Chemistry, M.M.U College of Pharmacy. K.K. Doddi, Ramanagara- 562159. Karnataka.

2. Department of Chemistry. Jawaharlal Nehru Technological University Anantapur, Ananthapuramu- 515002. Andhra Pradesh.


ABSTRACT

Considering the potential to be a lead molecule and having a wide variety of pharmacological activities like anti-inflammatory, anticancer, antihepatotoxic, antibacterial, antiviral etc., a series of bioactive γ-benzopyrone compounds were synthesized and analgesic activity was evaluated. The synthesized compounds were characterized by IR, 1H NMR and Mass spectral studies. Some of the compounds synthesized i.e. 4c, 4d, 4g and 4h showed appreciable analgesic activity.

Keywords: Acylation, condensation, amino derivatives.


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