ISSN 2321–3647
Sat, 18 Nov 2017

Evaluation of Setaria Italica Starch as Pharmaceutical Excipient

G. Usha rani1, K. Latha1, V. Neeharika1*

1. Faculty of Pharmacy, G. Pulla Reddy College of Pharmacy, Mehdipatnam, Hyderabad, India.


A study has been carried out to investigate the physicochemical, binding and disintegrating properties of millet starch obtained from Setaria italica (Family Gramineae). The isolated starch has been evaluated and characterized for various parameters like ash values, loss on drying, viscosity, amylose content and preformulation studies like sieve analysis, micrometry, flow properties, moisture content, compatability studies and compared with that of commercial available maize starch. The tablets were prepared by wet and dry granulation methods using drugs paracetamol and aspirin respectively with Setaria italica starch and maize starch as binder, disintegrant, binder and disintegrant and were evaluated. The results showed that Setaria italica starch employed in paracetamol tablets as binder(15%) and disintegrant(10%) and in aspirin tablets as binder(5%) and disintegrant(15%) concentrations produced hard and good quality tablets, comparable in friability, weight variation, disintegration and dissolution time to tablets produced with maize starch. The results indicate that Setaria italica starch can be employed as an alternative binder to maize starch in the formulation of paracetamol and aspirin tablets.

Keywords: Setaria italica starch, maize starch, binder, disintegrant and excipient.

[PDF]  Viewed: 692  Downloaded: 94
  • Call for paper
    Call for paper

    American Journal of Pharmacy and Health Research (AJPHR) is a peer-reviewed, monthly official international journal allowing access to abstracts and full-text.

  • Email & SMS Alerts
    Email & SMS Alerts

    Email/SMS alert system is one of the key features and gives update information about the submitted manuscript.


  • Article Statastics
    Article Statastics

    American Journal of Pharmacy and Health Research (AJPHR) provides unique facility for authors to know popularity of articles on basis of numbers of PDF download and views. It will display in tabulated format.

  • Online Submission
    Online Submission

    American Journal of Pharmacy and Health Research (AJPHR) is one of the International open access journal devoted to various disciplines in science and technology.


web counter
web counter