ISSN 2321–3647
Sun, 19 Nov 2017

Clinical Evaluation of Coded Herbal Medicine Fertinorm for the Treatment Female Infertility

Halima Nazar1*, Khan Usmanghani1

1.Department of Surgery and Allied Sciences and Department of Basic Medical Sciences Faculty of Eastern Medicine, Hamdard University, Karachi, Pakistan


ABSTRACT

The aim and objective was to analyze the comparative efficacy between Fertinorm (herbal medicine) and Clomiphene citrate (allopathic medicine) for the treatment of female anovulatory infertility. A double blind, prospective, randomized two arm parallel groups clinical trial was conducted in WHO group II anovulatory female patients. The trial was executed on 200 subjects of ages between 20-37 years in four consecutive cycles. End results data analysis revealed no significant efficacy difference between two treatment arms as p > 0.005 and conception rate was same between these two groups however adverse effects were not seen in test group. In conclusion, on the basis of statistical analysis done by chi square test, Mann-Whitney U test and Kaplan-Meier method null hypothesis is accepted in female anovulatory infertility treatment (p>0.05) and strongly rejected with regard to safety as p<0.05. However, based on statistical analysis drawn by chi square test and Kendall's   tau-b test, significantly greater side effects were noted in group B as p = 0.001 and p = 0.028 respectively.

Keywords: Female anovulatory infertility, herbal alternate treatment, Clomiphene citrate therapy


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