ISSN 2321–3647
Sun, 19 Nov 2017

Formulation and evaluation of herbal Antitussive Syrup of Methanolic Extract of Lycopus europaeus in Mice

Abdul Aziz1*, Imran Ahmad Khan1, Aqsa Afzal1, Shaukat Hussain Munawar2

1. Faculty of Pharmacy, Bahauddin Zakariya University, Multan, Pakistan

2. Faculty of medicine and allied medical science, Isra University Islamabad, Pakistan


Methanolic extract of Lycopus europaeus were investigated for their antitussive effect on citric acid induced cough model in mice. The results showed that the formulated cough syrup exhibited significant antitussive activity in a dose dependent manner the activity was compared with the prototype antitussive agent diphenhydramine HCl. It has been observed that the extract has produced 54%, 70%, 75% reduction in cough bouts at the dose level of 1, 2, 3 ml respectively after 1hr of drug administration. It is evident from the data the highest dose of 3 ml was found to be more effective. It is found that antitussive activity produced by the herbal formulation in the minimum dose was much better than the standard drug.

Keysword: Antitussive agent, Polyherbal cough syrup, Diphenhydramine HCl, Citric acid induced.

[PDF]  Viewed: 3869  Downloaded: 1571
  • Call for paper
    Call for paper

    American Journal of Pharmacy and Health Research (AJPHR) is a peer-reviewed, monthly official international journal allowing access to abstracts and full-text.

  • Email & SMS Alerts
    Email & SMS Alerts

    Email/SMS alert system is one of the key features and gives update information about the submitted manuscript.


  • Article Statastics
    Article Statastics

    American Journal of Pharmacy and Health Research (AJPHR) provides unique facility for authors to know popularity of articles on basis of numbers of PDF download and views. It will display in tabulated format.

  • Online Submission
    Online Submission

    American Journal of Pharmacy and Health Research (AJPHR) is one of the International open access journal devoted to various disciplines in science and technology.


web counter
web counter