ISSN 2321–3647
Sun, 19 Nov 2017

Azadirachta Indica and Aloe Vera Leaves Extracts Enhances Excision Wound Healing Activity

Shiv Kumar Purohit*1, Ratan Lal Soni1, Renu Solanki2

1. College of Veterinary and Animal Science, Rajasthan

2. Lachoo Memorial College of Science and technology, Pharmacy Wing, Rajasthan


ABSTRACT

Wounds are major responsible for physical disabilities. Wound disease spread by the invasion of bacteria inside the body through skin. Most of pathogenic microorganisms responsible for wound include Staphylococcus aureus, Streptococcus pyogenes, Enterococci, Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa. Bacterial infections on skin are the common ailment for generation of other diseases in the body. Wound infections represent the invasion of tissues by number of species of microorganisms. These infections disturb the immune system of body and cause delayed wound healing. Aloe vera leaves pulp is used for medicinal purposes, including treatment of constipation, asthma, diabetes, peptic ulcer, inflammation, wound healing, heart burn, heat stroke etc. While Azadirachta indica is useful in tiredness, cough, fever, loss of appetite, worm infestation. It heals wound, heat-rash, boils, jaundice, leprosy, skin disorders, eye disorders, stomach ulcers, chicken pox, excessive thirst, diabetes and insect poisons. It act as anti-leprotic, antimalarial, anti-hemorrhoidal and anthelmintic agent. The present study was undertaken on evaluation of combinational effect of ethanolic extract of Aloe vera leaves pulp and Azadirachta indica leaves for wound healing activity through topical route on excision wound model. The activity was compared with standard drug Povidone Iodine ointment(5% w/w). Combinational effect of both extract was showed faster wound healing effect than standard drug Povidone Iodine ointment on excision wound model.

Keywords: Aloe vera, Azadirachta indica, povidone iodine ointment, wound healing activity, excision wound model.


[PDF]  Viewed: 1320  Downloaded: 181
  • Call for paper
    Call for paper

    American Journal of Pharmacy and Health Research (AJPHR) is a peer-reviewed, monthly official international journal allowing access to abstracts and full-text.

  • Email & SMS Alerts
    Email & SMS Alerts

    Email/SMS alert system is one of the key features and gives update information about the submitted manuscript.

    Read more...

  • Article Statastics
    Article Statastics

    American Journal of Pharmacy and Health Research (AJPHR) provides unique facility for authors to know popularity of articles on basis of numbers of PDF download and views. It will display in tabulated format.

  • Online Submission
    Online Submission

    American Journal of Pharmacy and Health Research (AJPHR) is one of the International open access journal devoted to various disciplines in science and technology.

    Read more...

web counter
web counter