ISSN 2321–3647
Sun, 19 Nov 2017

Penetration and Identification of Drug Use and Abuse in Hair by Various Advanced Analytical Techniques

Jitendra S Patel1*, Toral V Patel1, Shreena N Khant1, Sandip Dholakia1, Madhabhai M Patel1

1.Shankersinh Vaghela Bapu Institute of Pharmacy, Vasan, Gandhinagar, 382650


ABSTRACT

Now a days, besides blood, urine, saliva & hair is being recognized as an alternative & fundamental biological specimen for drug testing in the field of forensic analysis & clinical chemistry. Hair testing was used in legal cases, historical researches. This review on methodologically & practically used to the application of hair as a biological indication of drug use & abuse. The mechanism of drug incorporation into the hair were commented. This article include sample (hair) collection, preparation & extraction methods as well as the advanced analytical techniques such as immunoassay, HPLC-CE, GC-LC & GC-MS/MS. The outcome of hair analysis had been review for this categories: drugs of abuse(Opiates, Cocaines. Amphetamine, Cannabinoids) & Benzodizapines, prescribed drugs etc. finally the specific purpose of hair testing was discussed along with their interpretation.

Keywords: hair, drugs of abuse, prescribed drugs, advanced analytical techniques. 


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